Article

T-cell-restricted intracellular antigen 1 regulates the expression and alternative splicing of stress-related genes in human renal tubular epithelial cells

2023-07-13

Abstract excerpt

Understanding the mechanisms mediating secondary nonimmune renal injury in lupus nephritis (LN) is important for therapeutic development. Cytotoxic granule-associated RNA-binding protein 1 (T-cell-resrticted intracellular antigen 1, TIA1) plays potential roles in infiltrating immune cells in LN. However, the regulatory targets and mechanisms underlying TIA1 activity in renal nonimmune cells remain unclear. Here, T...

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Literature Corpus work: fbad93cc-f5c5-538b-a020-26845662a09a
DOI: 10.21203/rs.3.rs-3150048/v1

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