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Article

The relationship between cell apoptosis dysfunction and FEN1 E160D mutation in lupus nephritis patients.

Autoimmunity - 1 Dec 2017

Wang Jing, Cao Ping, Qi Yuan-Yuan, Chen Xue-Ping, Ma Li, Deng Rong-Rong, Zhang Li-Li, Zhao Yu

Abstract excerpt

OBJECTIVE: This study aims to evaluate the role of FEN1 E160D mutation in lupus nephritis (LN) patients with cell apoptosis dysfunction. METHODS: (1) Cell apoptosis was detected from 50 paraffin samples obtained from renal biopsies of patients with Class IV LN by TUNEL method and the relationship of the systemic lupus erythematosus disease activity index 2000 (SLEDAI 2000) and renal tissue cell apoptotic index...

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Source

Identifiers

PMID: 29239254
DOI: 10.1080/08916934.2017.1402302

Genes

FEN1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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