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The causal relationship between gut microbiome composition and Alzheimer’s disease: A two-sample Mendelian randomization analysis

2025-08-21

Abstract excerpt

<h4>Background</h4> The gut microbiome has been linked to multiple complex human traits and diseases, including Alzheimer’s disease (AD). However, it is unclear from existing studies whether these relationships are causal. <h4>Methods</h4> Two-sample bidirectional Mendelian randomisation (MR) was used to explore the causal relationship between the human gut microbiome with AD risk and two markers of cognitive fu...

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Literature Corpus work
fba6bc53-b77c-5b7c-8d43-2dde9aa448e2
DOI
10.1101/2025.08.20.25333769
Open publication

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The causal relationship between gut microbiome composition and Alzheimer’s disease: A two-sample Mendelian randomization analysisDOI 10.1101/2025.08.20.25333769
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