Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Can early gut microbiota screening reduce the incidence of cognitive impairment? A Mendelian randomization study.

Journal of Alzheimer's disease : JAD - 1 Nov 2024

Xi Chongcheng, Zhang Jie, Liu Haihui, Xing Jia, Ding Yiyun, Wei Wei, Wang Le, Liu Zhenzhu

Abstract excerpt

Background: Gastrointestinal symptoms are now detected early in the clinical course of many dementia patients, and studies of the microbiome-gut-brain axis have confirmed bidirectional interactions between the gut and the brain. However, the causal relationship between gut microbiota and cognitive impairment has not been fully established. Therefore, this study conducted a bidirectional Mendelian randomization...

Topics

Join the communities discussing this publication.

Cognitive Dysfunction
Gastrointestinal Microbiome
Genome-Wide Association Study
Incidence
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39497320
DOI: 10.3233/JAD-231457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Can early gut microbiota screening reduce the incidence of cognitive impairment? A Mendelian randomization study.PMID 39497320Read ↗

Causal relationship between gut microflora and dementia: a Mendelian randomization studySemantic proximity Read ↗

Investigating Causal Associations between the Gut Microbiota and Dementia: A Mendelian Randomization StudySemantic proximity Read ↗

The causal relationship between gut microbiome composition and Alzheimer’s disease: A two-sample Mendelian randomization analysisSemantic proximity Read ↗

Causal Associations Between Gut Microbiota, Gut Microbiota-Derived Metabolites, and Alzheimer's Disease: A Multivariable Mendelian Randomization Study.Semantic proximity Read ↗

Genetic prediction of blood metabolites mediating the relationship between gut microbiota and Alzheimer’s disease: a Mendelian randomization studySemantic proximity Read ↗

Gut Microbiota and Targeted Biomarkers Analysis in Patients With Cognitive ImpairmentSemantic proximity Read ↗

Revealing the link between gut microbiota and brain tumor risk: a new perspective from Mendelian randomizationSemantic proximity Read ↗

Dissecting the Association between Gut Microbiota and Brain Structure Change Rate: A Two-Sample Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

Genetic risk of Alzheimer’s disease is partially mediated by gut bacteria compositionSemantic proximity Read ↗

Unraveling the connection between gut microbiota and Alzheimer’s disease: a two-sample Mendelian randomization analysisSemantic proximity Read ↗

Association of the Gut Microbiota With Cognitive Function in MidlifeSemantic proximity Read ↗

Investigating Casual Associations among Gut Microbiota, Metabolites and Neurodegenerative Diseases: A Mendelian Randomization StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.