Article

Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

2019-02-21

Abstract excerpt

Claudin-low breast cancer is a molecular subtype associated with poor prognosis and without targeted treatment options. The claudin-low subtype is defined by certain biological characteristics, some of which may be clinically actionable, such as high immunogenicity. In mice, the medroxyprogesterone acetate (MPA) and 7,12-dimethylbenzanthracene (DMBA) induced mammary tumor model yields a heterogeneous set of tumors...

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Literature Corpus work: fb537143-b3e8-5d47-adf4-7101eb5938cb
DOI: 10.1101/557298

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