Article

Primary aldosteronism results in a decline estimated glomerular filtration rate independent of blood pressure: evidence from a case-control and mendelian randomization study

2024-09-09

Abstract excerpt

ABSTRACT Background: Primary aldosteronism (PA) is the predominant cause of secondary hypertension, leading to cardiovascular and renal damage via mechanisms such as oxidative stress and fibrosis. However, current epidemiology findings on the association between PA and estimated glomerular filtration rate (eGFR) remain inconsistent. <h4>Methods:</h4> A 1:1 sex- and age-matched case-control study was conducted amon...

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Literature Corpus work: fb3a455a-88ed-527c-b78a-44c4fa32e7d9
DOI: 10.1101/2024.09.08.24313278

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