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Beyond Blood Pressure: Emerging Pathways and Precision Approaches in Hypertension-Induced Kidney Damage

6 Aug 2025

Abstract excerpt

Recent studies have demonstrated that the development and progression of hypertensive kidney injury comprise not only elevated systemic blood pressure but also a complex interplay of cellular, molecular, and genetic mechanisms. In this report, we outline the key emerging pathways-ranging from dysregulated renin-angiotensin system signaling, oxidative stress, immune-mediated inflammation, and metabolic...

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PMID: 40806733
DOI: 10.3390/ijms26157606

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