Article

Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

2021-05-31

Abstract excerpt

The prevalence of Alzheimer’s disease (AD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD) is higher among patients with somatic insulinopathies, like metabolic syndrome (MetS), obesity, and type 2 diabetes mellitus (T2DM). Dysregulation of insulin signalling has been implicated in these neuropsychiatric disorders, and shared genetic factors might partly underlie these observed comorbiditi...

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Literature Corpus work: fb19c4b1-d975-5d28-85c3-be7dba8388b7
DOI: 10.1101/2021.05.28.21258000

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