Article
Eight challenges in phylodynamic inference.
Epidemics - 1 Mar 2015
Frost Simon D W, Pybus Oliver G, Gog Julia R, Viboud Cecile, Bonhoeffer Sebastian, Bedford Trevor
Abstract excerpt
The field of phylodynamics, which attempts to enhance our understanding of infectious disease dynamics using pathogen phylogenies, has made great strides in the past decade. Basic epidemiological and evolutionary models are now well characterized with inferential frameworks in place. However, significant challenges remain in extending phylodynamic inference to more complex systems. These challenges include...
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