Identification of Marker Genes in Infectious Diseases from ScRNA-seq Data Using Interpretable Machine Learning

Abstract excerpt

A common result of infection is an abnormal immune response, which may be detrimental to the host. To control the infection, the immune system might undergo regulation, therefore producing an excess of either pro-inflammatory or anti-inflammatory pathways that can lead to widespread inflammation, tissue damage, and organ failure. A dysregulated immune response can manifest as changes in differentiated immune cell...

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