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Impact of Preanalytical and Analytical Methods on Cell-Free DNA Diagnostics

6 Sept 2021

Abstract excerpt

While tissue biopsy has for the longest time been the gold-standard in biomedicine, precision/personalized medicine is making the shift toward liquid biopsies. Cell-free DNA (cfDNA) based genetic and epigenetic biomarkers reflect the molecular status of its tissue-of-origin allowing for early and non-invasive diagnostics of different pathologies. However, selection of preanalytical procedures (including cfDNA...

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PMID: 34552921
DOI: 10.3389/fcell.2021.686149

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