Article

Host Genetic Background Effect on Body Weight Changes Influenced by <em>Smad</em>4 Knockout Using Collaborative Cross Mouse Population

2023-09-29

Abstract excerpt

<h4>Background: </h4> Obesity and its attendant conditions have become major health problems worldwide and is currently ranked as the fifth most common leading cause of death globally. Complex environmental and genetic factors are the cause of the current obesity epidemic. Diet, lifestyle, chemical exposures, and other confounding factors are difficult to manage in humans. The mice model is helpful in researching...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fab43f01-6465-5620-9538-31348a2ff8a0
DOI: 10.20944/preprints202309.2084.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Host Genetic Background Effect on Body Weight Changes Influenced by <em>Smad</em>4 Knockout Using Collaborative Cross Mouse PopulationDOI 10.20944/preprints202309.2084.v1Read

Unraveling the Host Genetic Background Effect on Internal Organ Weight Influenced by Obesity and Diabetes Using Collaborative Cross MiceSemantic proximity Read

Host Genetic Background Affects the Brain Weight Influenced by Obesity and Diabetes Development in Collaborative Cross MiceSemantic proximity Read

Container-aided Integrative QTL and RNA-seq Analysis of Collaborative Cross Mice Supports Distinct Sex-Oriented Molecular Modes of Response in ObesitySemantic proximity Read

Age and diet shape the genetic architecture of body weight in Diversity Outbred miceSemantic proximity Read

Advances in comparative genetics: influence of genetics on obesity.Semantic proximity Read

High-fat-diet induced development of increased fasting glucose levels and impaired response to intraperitoneal glucose challenge in the collaborative cross mouse genetic reference population.Semantic proximity Read

Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity.Semantic proximity Read

Mapping QTL underlying body weight changes that act at different times during high-fat diet challenge in collaborative cross miceSemantic proximity Read

Fifteen years of the Diversity Outbred mouse model: a review.Semantic proximity Read

How mice are indispensable for understanding obesity and diabetes genetics.Semantic proximity Read

Genetic Background Shapes Phenotypic Response to Diet for Adiposity in the Collaborative CrossSemantic proximity Read

Using mouse models to dissect the genetics of obesity.Semantic proximity Read