Article

Container-aided Integrative QTL and RNA-seq Analysis of Collaborative Cross Mice Supports Distinct Sex-Oriented Molecular Modes of Response in Obesity

2020-10-12

Abstract excerpt

<title>Abstract</title> <p>Background: The Collaborative Cross (CC) mouse population is a valuable resource to study the genetic basis of complex traits, such as obesity. Although the development of obesity is influenced by environmental factors, underlying genetic mechanisms play a crucial role in the response to these factors. The interplay between the genetic background and the gene expression pattern can prov...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1797cc0c-1eba-5e70-91a2-a6b56faf462d
DOI: 10.21203/rs.2.13505/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Container-aided Integrative QTL and RNA-seq Analysis of Collaborative Cross Mice Supports Distinct Sex-Oriented Molecular Modes of Response in ObesityDOI 10.21203/rs.2.13505/v3Read

Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity.Semantic proximity Read

Host Genetic Background Effect on Body Weight Changes Influenced by <em>Smad</em>4 Knockout Using Collaborative Cross Mouse PopulationSemantic proximity Read

Unraveling the Host Genetic Background Effect on Internal Organ Weight Influenced by Obesity and Diabetes Using Collaborative Cross MiceSemantic proximity Read

Advances in comparative genetics: influence of genetics on obesity.Semantic proximity Read

Host Genetic Background Affects the Brain Weight Influenced by Obesity and Diabetes Development in Collaborative Cross MiceSemantic proximity Read

High-fat-diet induced development of increased fasting glucose levels and impaired response to intraperitoneal glucose challenge in the collaborative cross mouse genetic reference population.Semantic proximity Read

Mapping QTL underlying body weight changes that act at different times during high-fat diet challenge in collaborative cross miceSemantic proximity Read

The Effects of Sex and Diet on Physiology and Liver Gene Expression in Diversity Outbred MiceSemantic proximity Read

Glucose tolerance female-specific QTL mapped in collaborative cross mice.Semantic proximity Read

A novel computational framework to identify translational potential of genetic mouse models in rare genetic obesitySemantic proximity Read

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in miceSemantic proximity Read

Modeling metabolic disease susceptibility and resilience in genetically diverse miceSemantic proximity Read