Article

Polygenic Risk and Rare Variants in Endotypes of Idiopathic Pulmonary Fibrosis

2025-05-23

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Idiopathic pulmonary fibrosis (IPF) and telomere length (TL) are both strongly linked to rare and common genetic variation. Shortened TL itself may be causal for IPF. Whether rare and common variants compete or cooperate to confer genetic risk of IPF uniformly is unknown. <h4>Methods</h4> We used whole genome sequencing (WGS) data from a discovery case-control cohort sequenced...

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Literature Corpus work: fab3f0e8-e6d7-54d3-957a-59cb652393e9
DOI: 10.1101/2025.05.22.25328177

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