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Article

Utility of whole genome sequencing in assessing risk and clinically relevant outcomes for pulmonary fibrosis.

The European respiratory journal - 1 Dec 2022

Zhang David, Newton Chad A, Wang Binhan, Povysil Gundula, Noth Imre, Martinez Fernando J, Raghu Ganesh, Goldstein David, Garcia Christine Kim

Abstract excerpt

BACKGROUND: Whole genome sequencing (WGS) can detect variants and estimate telomere length. The clinical utility of WGS in estimating risk, progression and survival of pulmonary fibrosis patients is unknown. METHODS: In this observational cohort study, we performed WGS on 949 patients with idiopathic pulmonary fibrosis or familial pulmonary fibrosis to determine rare and common variant genotypes, estimate...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobinopathies and Related Disorders

Share to Idiopathic Pulmonary Fibrosis

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Share to Telomeres, Telomerase, and Senescence

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Source

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Identifiers

PMID: 36028256
DOI: 10.1183/13993003.00577-2022
PMCID: PMC10038316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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