Article

TGF-β Mediated Cell Adhesion Dynamics and Epithelial to Mesenchymal Transition in 3D and 2D Ovarian Cancer Models

2018-11-08

Abstract excerpt

<h4>Background</h4> Three-dimensional (3D) tumor cultures in vitro have recently regained attention as they have been acclaimed to have higher similarity to in vivo tumors than cells grown in conventional monolayers (2D). Cancer cells in 2D monolayers fail to mimic the exact tumor microenvironment existing in the real clinical samples. The 3D anchorage-independent cancer models can better explain the cell adhes...

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Literature Corpus work: fa888ec7-9bdc-5e3e-984f-a85e70d0e624
DOI: 10.1101/465617

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