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Article

Cross-Talk between the TGF-β and Cell Adhesion Signaling Pathways in Cancer

1 Jan 2024

Abstract excerpt

Transforming growth factor-β (TGF-β) is strongly associated with the cell adhesion signaling pathway in cell differentiation, migration, etc. Mechanistically, TGF-β is secreted in an inactive form and localizes to the extracellular matrix (ECM) via the latent TGF-β binding protein (LTBP). However, it is the release of mature TGF-β that is essential for the activation of the TGF-β signaling pathway. This progress...

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PMID: 38818471
DOI: 10.7150/ijms.96274

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