Article

Single-cell transcriptome analysis reveals the targeting of epithelial and fibroblast interactions in ovarian cancer

2026-02-16

Abstract excerpt

<title>Abstract</title> <p>Background Ovarian clear cell carcinoma (OCCC), a therapy-refractory epithelial ovarian cancer subtype with distinct tumor microenvironment (TME) features, has unclear links between cancer-associated fibroblasts (CAFs), extracellular matrix (ECM) remodeling (especially collagen deposition) and disease progression. Methods We characterized TME via single-cell RNA sequencing of 10 fresh...

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Literature Corpus work: 7479a50f-e985-5ccd-a062-fef22540ee30
DOI: 10.21203/rs.3.rs-8586120/v1

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