Article

Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2

2022-11-22

Abstract excerpt

SARS-CoV-2 can infect human cells through the recognition of the human angiotensin-converting enzyme 2 (ACE2) receptors. This affinity is given by six amino acid located in the receptor binding domain (RBD) region within the Spike protein. Genetic recombination involving bat and pangolin Sarbecoviruses , and natural selection have been proposed as possible explanations for the acquisition of these amino acids. In...

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Literature Corpus work: fa7bf23b-6027-5e18-9c9c-8ce5028223ce
DOI: 10.21203/rs.3.rs-2189993/v1

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