Article

Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

2020-02-18

Abstract excerpt

The emergence of SARS-CoV-2 underscores the need to better understand the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. In the betacoronavirus genus, which also includes SARS-CoV and MERS-CoV, recombination frequently encompasses the Receptor Binding Domain (RBD) of the Spike protein, which, in turn, is responsible for viral binding to host cell receptors. Here, we f...

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Literature Corpus work: e5257612-933b-59f1-ab63-344154384899
DOI: 10.1101/2020.02.10.942748

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