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SHCBP1 interacting with  EOGT enhanced O-GlcNAcylation of NOTCH1 and promoted the development of pancreatic cancer .

2020-10-27

Abstract excerpt

<title>Abstract</title> <p>Background: Pancreatic cancer(PDAC) remains one of the most lethal cancers worldwide, The accumulation of many abnormal epigenetic abnormalities contribute to the fatal prognosis of PDAC,While available studies are still limited. Many studies have confirmed that the Shc SH2-domain binding protein 1(SHCBP1) plays as proto-oncogene in cancers. However, whether SHCBP1 plays a role in pancr...

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Literature Corpus work
67b9dafc-c6c6-5ef1-b85c-f9d4f57d2858
DOI
10.21203/rs.3.rs-95104/v1
Open publication

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SHCBP1 interacting with EOGT enhanced O-GlcNAcylation of NOTCH1 and promoted the development of pancreatic cancer .DOI 10.21203/rs.3.rs-95104/v1
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