Article

Fragment-based approaches to targeting EthR from mycobacterium tuberculosis

2019-01-01

Abstract excerpt

Tuberculosis affects millions of people worldwide every year. The current treatment for TB is divided into a regimen of both first- and second-line drugs, where first-line treatments are more tolerated and require shorter treatment lengths. With rising levels of resistance, alternative treatment regimes are urgently needed to fight this disease. Ethionamide, a second-line drug is administered as a prodrug which is...

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Literature Corpus work: f99f97c1-147d-5b26-85d8-19dc487771b3
DOI: 10.17863/cam.37485

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