Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins

1 Oct 2018

Abstract excerpt

Objective: microRNAs are regulatory molecules regarded as important in the pathogenesis of different types of tumors. microRNA-216a (miR-216a-5p) has been identified as a tumor suppressor in multiple malignancies. However, the role of miR-216a-5p in the pathogenesis of small cell lung cancer (SCLC) remains obscure. The objective of this study was to investigate the role of the miR-216a-5p/Bcl-2 axis in SCLC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Lung Cancer Research Studies
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30425570
DOI: 10.2147/cmar.s178380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteinsPMID 30425570Read ↗

MicroRNA-148b regulates tumor growth of non-small cell lung cancer through targeting MAPK/JNK pathwaySemantic proximity Read ↗

MiR-486-5p specifically suppresses SAPCD2 expression, which attenuates the aggressive phenotypes of lung adenocarcinoma cells.Semantic proximity Read ↗

MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosisSemantic proximity Read ↗

miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2Semantic proximity Read ↗

miR-196b-5p Promotes Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells via Targeting RSPO2Semantic proximity Read ↗

A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancerSemantic proximity Read ↗

Function of miR-200a in proliferation and apoptosis of non-small cell lung cancer cellsSemantic proximity Read ↗

Downregulation of LANCL1-AS1 Promotes Tumorigenesis in Lung Adenocarcinoma Via the Modulation of miR-6748a-3p/PRSS8 AxisSemantic proximity Read ↗

Long non-coding RNA CCAT1 promotes non-small cell lung cancer progression by regulating the miR-216a-5p/RAP2B axis.Semantic proximity Read ↗

LINC00346 Sponges miR-30c-2-3p to Promote the Development of Lung Adenocarcinoma by Targeting MYBL2 and Regulating CELL CYCLE Signaling PathwaySemantic proximity Read ↗

NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy processSemantic proximity Read ↗

miR-486-3p Suppresses Malignant Phenotypes and is Associated with Reduced WNT5B, DVL1, and β-catenin Expression in Lung Adenocarcinoma Cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.