Article
Apoptosis and lung cancer: a review.
Journal of cellular biochemistry - 1 Apr 2003
Shivapurkar Narayan, Reddy Jyotsna, Chaudhary Preet M, Gazdar Adi F
Abstract excerpt
It is important to understand the molecular events that contribute to drug-induced apoptosis, and how tumors evade apoptotic death. Defects in apoptosis are implicated in both tumorigenesis and drug resistance, and these defects are cause of chemotherapy failures. These studies should explain the relationship between cancer genetics and treatment sensitivity, and should enable a more rational approach to...
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