Article

Common Intra-Articular T Cell Expansions in Patients with Reactive Arthritis: Identical β-Chain Junctional Sequences and Cytotoxicity Toward HLA-B27

1999-04-01

Abstract excerpt

Abstract Spondyloarthropathies constitute a group of autoimmune diseases of special interest because of their tight association with the MHC class I molecule HLA-B27 and the bacterial triggering of some clinical forms called reactive arthritis (ReA). One current hypothesis is the presentation by HLA-B27 of a so-called arthritogenic peptide to T cells. To better focus on the relevant T cell populations within the j...

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Literature Corpus work: f947f6c0-8df4-5759-bbc9-9e6a47ef890f
DOI: 10.4049/jimmunol.162.7.3830

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