Article

The combination of elesclomol and Cu2+ can inhibit the growth of colon cancer cells by targeting FDX1

2023-10-31

Abstract excerpt

<title>Abstract</title> <p>Background Colon adenocarcinoma (COAD) is the predominant histological type of colon cancer. Elesclomol, a unique copper ion carrier, is considered a potential anticancer drug and has been the subject of a series of clinical trials. FDX1 is the intended target of elesclomol and is believed to be a key regulatory factor in copper-mediated cell death. Through its specific targeting of FD...

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Literature Corpus work: f93e9e60-cf18-5cb4-b7dc-73d6973abcce
DOI: 10.21203/rs.3.rs-3505099/v1

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