Article

Bayesian Metamodeling of pancreatic islet architecture and functional dynamics

2021-11-08

Abstract excerpt

The pancreatic islet (islet of Langerhans) is a mini-organ comprising several thousand endocrine cells, functioning jointly to maintain normoglycemia. Cellular networks within an islet were shown to influence its function in health and disease, but there are major gaps in our quantitative understanding of such architecture-function relations. Comprehensive modeling of an islet architecture and function requires th...

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Literature Corpus work: f8f7b99c-54b4-53e6-81fa-c8824606cebd
DOI: 10.1101/2021.11.07.467656

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