Article

Longitudinal peripheral blood transcriptional analysis of COVID-19 patients captures disease progression and reveals potential biomarkers

2020-05-08

Abstract excerpt

<h4>ABSTRACT</h4> COVID-19, caused by SARS-CoV-2, is an acute self-resolving disease in most of the patients, but some patients can develop a severe illness or even death. To characterize the host responses and identify potential biomarkers during disease progression, we performed a longitudinal transcriptome analysis for peripheral blood mononuclear cells (PBMCs) collected from 4 COVID-19 patients at 4 different...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c7b9cb2c-e44c-551c-a003-c4497c9bee70
DOI: 10.1101/2020.05.05.20091355

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Longitudinal peripheral blood transcriptional analysis of COVID-19 patients captures disease progression and reveals potential biomarkersDOI 10.1101/2020.05.05.20091355Read

Long Term Longitudinal Analysis of Peripheral Blood Transcriptome in COVID-19 PatientsSemantic proximity Read

Transcriptomic profiling of disease severity in patients with COVID-19 reveals role of blood clotting and vasculature related genesSemantic proximity Read

Characterisation of the blood RNA host response underpinning severity in COVID-19 patientsSemantic proximity Read

Single-cell RNA sequencing reveals HIF1A as a severity-sensitive immunological scar in circulating monocytes of convalescent comorbidity-free COVID-19 patientsSemantic proximity Read

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patientsSemantic proximity Read

Characterisation of the blood RNA host response underpinning severity in COVID-19 patientsSemantic proximity Read

Dysregulated transcriptional responses to SARS-CoV-2 in the peripherySemantic proximity Read

Identification of PBMC-based molecular signature associational with COVID-19 disease severitySemantic proximity Read

Comprehensive Transcriptomic Analysis of COVID-19 Blood, Lung, and AirwaySemantic proximity Read

Transcriptomic Similarities and Differences in Host Response between SARS-CoV-2 and Other Viral InfectionsSemantic proximity Read

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approachesSemantic proximity Read

A blood-based comprehensive and systems-level analysis of disease stages, immune regulation and symptoms in COVID-19 patientsSemantic proximity Read