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Alterations in Circulating Monocytes Predict COVID-19 Severity and Include Chromatin Modifications Still Detectable Six Months after Recovery

17 Sept 2021

Abstract excerpt

An early analysis of circulating monocytes may be critical for predicting COVID-19 course and its sequelae. In 131 untreated, acute COVID-19 patients at emergency room arrival, monocytes showed decreased surface molecule expression, including low HLA-DR, in association with an inflammatory cytokine status and limited anti-SARS-CoV-2-specific T cell response. Most of these alterations had normalized in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34572439
DOI: 10.3390/biomedicines9091253

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