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Article

Unraveling transcriptome dynamics in human spermatogenesis

22 Sept 2017

Abstract excerpt

Spermatogenesis is a dynamic developmental process that includes stem cell proliferation and differentiation, meiotic cell divisions and extreme chromatin condensation. Although studied in mice, the molecular control of human spermatogenesis is largely unknown. Here, we developed a protocol that enables next-generation sequencing of RNA obtained from pools of 500 individually laser-capture microdissected cells of...

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PMID: 28935708
DOI: 10.1242/dev.152413

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