Article

A deep learning framework for predicting human essential genes from population and functional genomic data

2021-12-23

Abstract excerpt

Being able to predict essential genes intolerant to loss-of-function (LOF) mutations can dramatically improve our ability to identify genes associated with genetic disorders. Numerous computational methods have recently been developed to predict human essential genes from population genomic data; however, the existing methods have limited power in pinpointing short essential genes due to the sparsity of polymorphi...

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Literature Corpus work: f889474a-8b54-5a9e-ae30-6c3c222acd64
DOI: 10.1101/2021.12.21.473690

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