Article

On the Relation of Gene Essentiality to Intron Structure: A Computational and Deep Learning Approach

2020-04-01

Abstract excerpt

Identification and study of human-essential genes has become of practical importance with the realization that disruption or loss of nearby essential genes can introduce latent-vulnerabilities to cancer cells. Essential genes have been studied by copy-number-variants and deletion events, which are associated with introns. The premise of our work is that introns of essential genes have characteristic properties tha...

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Literature Corpus work: dc9573de-70c6-5e2e-a61f-33f96541b3f3
DOI: 10.1101/2020.03.31.019125

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