Article

The molecular chaperone Cysteine String Protein is required to stabilize <i>trans</i> -SNARE complexes during human sperm acrosomal exocytosis

2022-03-04

Abstract excerpt

Membrane fusion in sperm cells is crucial for acrosomal exocytosis and must be preserved to assure fertilizing capacity. Evolutionarily conserved protein machinery regulates acrosomal exocytosis. Molecular chaperones play a vital role in spermatogenesis and post-testicular maturation. Cysteine String Protein (CSP) is a member of the Hsp40 co-chaperones, and for more than 20 years, most research published focused o...

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Literature Corpus work: f84239ee-d0ee-5951-85ce-c24ee0282a02
DOI: 10.1101/2022.03.03.482836

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