Article
The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble intrans-complexes during human sperm acrosomal exocytosis
29 Oct 2022
Abstract excerpt
Membrane fusion in sperm cells is crucial for acrosomal exocytosis and must be preserved to ensure fertilizing capacity. Evolutionarily conserved protein machinery regulates acrosomal exocytosis. Molecular chaperones play a vital role in spermatogenesis and post-testicular maturation. Cysteine string protein (CSP) is a member of the Hsp40 co-chaperones, and the participation of molecular chaperones in acrosomal...
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