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Epididymosomes: transfer of fertility-modulating proteins to the sperm surface

1 Jan 2015

Abstract excerpt

A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation. These proteins serve roles in immunoprotection and in key steps of fertilization such as capacitation, acrosomal exocytosis and sperm-egg interactions. Their acquisition on sperm cells is mediated both by membrane vesicles (epididymosomes, EP) which were first...

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PMID: 26112481
DOI: 10.4103/1008-682x.155538

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