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Article

Genomic and immunological differences in endometrial cancer: a comparative study between young and old Asian patients.

Frontiers in immunology - 1 Jan 2026

Jiang Senwei, Li Yunhui, Wu Shanshan, Wan Jing, Li Xiaomao

Abstract excerpt

Background: Endometrial carcinoma (EC) demonstrates a pronounced age-related disparity in clinical outcomes, yet the underlying genomic and molecular mechanisms remain incompletely characterized, especially across Asian populations. Methods: We performed an integrated genomic analysis of two independent cohorts: the MSK-MET Asian cohort (n=94) and a Chinese EC cohort, EC-3rd-SYSU (n=18). Patients were stratified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41743739
DOI: 10.3389/fimmu.2026.1737794
PMCID: PMC12929549

Genes

PTEN
ARID1A
MET
TP53
CTNNB1
FGFR2
KRAS
MSH6
PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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