Article

Chromomycin A <sub>5</sub> induces bonafide immunogenic cell death in metastatic melanoma

2021-09-20

Abstract excerpt

Some first-line cytotoxic chemotherapics, e.g. doxorubicin, paclitaxel and oxaliplatin, induce activation of the immune system through immunogenic cell death (ICD). Tumor cells undergoing ICD function as a vaccine, releasing damage-associated molecular patterns (DAMPs), which act as adjuvants, and neoantigens of the tumor are recognized as antigens. ICD induction is rare, however it yields better and long-lasting...

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Literature Corpus work: bdd65740-8797-5629-93dd-a057a66c6cc8
DOI: 10.1101/2021.09.18.460876

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