Article

Quantitative imaging of plasmid DNA in human airway epithelial cells following non-viral gene transfer

2013-01-01

Abstract excerpt

The UK CF Gene Therapy Consortium is interested in non-viral gene therapy for cystic fibrosis (CF). To provide insight into the intracellular bottlenecks plasmid DNA (pDNA) encounters on its way to the nuclei of airway epithelial cells, I sought to quantitatively describe the intracellular fate of non-virally transferred pDNA using a clinically relevant human airway epithelial cell air-liquid-interface (ALI) model...

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Literature Corpus work: f81d1f11-5992-5a15-9499-d609c2821795
DOI: 10.25560/73141

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