Limitations of the murine nose in the development of nonviral airway gene transfer.

doi:10.1165/rcmb.2009-0075OC

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Article

Limitations of the murine nose in the development of nonviral airway gene transfer.

American journal of respiratory cell and molecular biology - 1 Jul 2010

Griesenbach Uta, Sumner-Jones Stephanie G, Holder Emma, Munkonge Felix M, Wodehouse Theresa, Smith Stephen N, Wasowicz Marguerite Y, Pringle Ian, Casamayor Isabel, Chan Mario, Coles Rebecca, Cornish Nikki, Dewar Ann, Doherty Ann, Farley Raymond, Green Anne-Marie, Jones Bryony L, Larsen Mia D B, Lawton Anna E, Manvell Michelle, Painter Hazel, Singh Charanjit, Somerton Lucinda, Stevenson Barbara, Varathalingam Anusha, Siegel Craig, Scheule Ronald K, Cheng Seng H, Davies Jane C, Porteous David J, Gill Deborah R, Boyd A Christopher, Hyde Steve C, Alton Eric W F W

Abstract excerpt

A clinical program to assess whether lipid GL67A-mediated gene transfer can ameliorate cystic fibrosis (CF) lung disease is currently being undertaken by the UK CF Gene Therapy Consortium. We have evaluated GL67A gene transfer to the murine nasal epithelium of wild-type and CF knockout mice to as...

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PMID: 19648474
DOI: 10.1165/rcmb.2009-0075OC

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CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19648474-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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