Article

STAT1 dissociates adipose tissue inflammation from insulin sensitivity in obesity

2020-04-12

Abstract excerpt

Obesity fosters low-grade inflammation in white adipose tissue (WAT) that may contribute to the insulin resistance that characterizes type 2 diabetes mellitus (T2DM). However, the causal relationship of these events remains unclear. The established dominance of signal transducer and activator of transcription 1 (STAT1) function in the immune response suggests an obligate link between inflammation and the co-morbid...

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Literature Corpus work: f819d937-4547-56bf-b928-c04fdc814246
DOI: 10.1101/2020.04.10.036053

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