Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adipose

5 Jul 2024

Abstract excerpt

OBJECTIVE: The objective of this study was to identify the transcriptional landscape of insulin resistance (IR) in subcutaneous adipose tissue (SAT) in humans across the spectrum of obesity. METHODS: We used SAT RNA sequencing in 220 individuals with metabolic phenotyping. RESULTS: We identified a 35-gene signature with high predictive accuracy for homeostatic model of IR that was expressed across a variety of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38967296
DOI: 10.1002/oby.24064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adiposePMID 38967296Read ↗

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in HumansSemantic proximity Read ↗

Characterisation of diabetes-associated adipose tissue dysfunction across the spectrum of body mass indexSemantic proximity Read ↗

Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin ResistanceSemantic proximity Read ↗

Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray studySemantic proximity Read ↗

Global Gene Expression Profiles of Subcutaneous Adipose and Muscle From Glucose-Tolerant, Insulin-Sensitive, and Insulin-Resistant Individuals Matched for BMISemantic proximity Read ↗

Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging.Semantic proximity Read ↗

The epigenetic signature of systemic insulin resistance in obese womenSemantic proximity Read ↗

The shifting of dominating roles between structural cells and immune cells are key regulators of human adipose tissues agingSemantic proximity Read ↗

Transcriptome of Subcutaneous Adipose Tissue reflect Membrane Dysfunction and Impaired Oxidative Processes in T2D across Heterogenous PopulationsSemantic proximity Read ↗

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytesSemantic proximity Read ↗

Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissueSemantic proximity Read ↗

The Transcriptomic Evidence on the Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indians Indicates the Involvement of BothSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.