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Article

A predictive insight into the ATRNL1-mediated ceRNA network driving abdominal aortic aneurysm progression via VSMC phenotypic switching.

Biochemical and biophysical research communications - 2 Jul 2026

Du Juan, Wang Xiaoyan, Wang Han, Wang Weiying, Zhang Yujie, Chao Yinping, Guan Hua, Xiang Aoqi, Chen Xiaochang, Su Peihong, Wang Chuan, Liu Jiping, Yu Qi, Zhang Lusha

Abstract excerpt

OBJECTIVE: Current therapeutic options for abdominal aortic aneurysm (AAA) are primarily invasive and carry significant risks, highlighting an urgent need for non-invasive pharmacological strategies. This study aimed to identify a novel ceRNA axis driving AAA progression and to explore potential therapeutic agents through systematic drug repositioning. METHODS: Transcriptomic data from human AAA (GSE183464) and a...

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Share to Aortic Aneurysm, Abdominal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42061003
DOI: 10.1016/j.bbrc.2026.153817

Genes

ATRNL1
LPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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