Article
Neurexins and neuropsychiatric disorders.
Neuroscience research - 1 Feb 2018
Kasem Enas, Kurihara Taiga, Tabuchi Katsuhiko
Abstract excerpt
Neurexins are a family of presynaptic single-pass transmembrane proteins that act as synaptic organizers in mammals. The neurexins consist of three genes (NRXN1, NRXN2, and NRXN3), each of which produces a longer α- and shorter β-form. Genomic alterations in NRXN genes have been identified in a wide variety of neuropsychiatric disorders, including autism spectrum disorders (ASD), schizophrenia, intellectual...
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