Article

Re-investigating the coughing rat model of pertussis to understand <i>Bordetella pertussis</i> pathogenesis

2021-04-03

Abstract excerpt

Bordetella pertussis ( Bp ) is a highly contagious bacterium that is the causative agent of whooping cough (pertussis). Currently, acellular pertussis vaccines (aP; DTaP; Tdap) are used to prevent pertussis disease. However, it is clear that the aP vaccine efficacy quickly wanes, resulting in the re-emergence of pertussis. Furthermore, recent work performed by the CDC suggest that current circulating strains are...

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Literature Corpus work: f795b7ec-e022-5fac-9db7-a876fbac0836
DOI: 10.1101/2021.04.02.438291

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