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Article

Nonhuman Primate and Human Challenge Models of Pertussis

13 Mar 2014

Abstract excerpt

Despite pertussis vaccination rates in excess of 95%, pertussis rates in the United States have been rising over the last 30 years, with increasingly larger outbreaks in 2004, 2010, and 2012. The reasons for this resurgence of pertussis are not clearly understood. The recent development of a baboon model of pertussis, along with the future development of a human challenge model of pertussis, has the potential to...

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PMID: 24626867
DOI: 10.1093/infdis/jit493

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