Article
Responses to Bordetella pertussis mutant strains and to vaccination in the coughing rat model of pertussis.
Journal of medical microbiology - 1 May 1994
Parton R, Hall E, Wardlaw A C
Abstract excerpt
Phase I strains 18-323, Tohama and L-84 of Bordetella pertussis produced paroxysmal coughing when encased in agarose beads and administered intrabronchially to adult Sprague-Dawley rats. In contrast, the Phase IV variant of strain L-84 was inactive in cough induction, as was strain BP 357, a transposon-insertion mutant which is deficient only in pertussis toxin (PT). Strain BPM 1809, which lacks only the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
