Article

Manifestations of Alzheimer’s Disease Genetic Risk in the Blood: A Cross-Sectional Multi-Omic Analysis in Healthy Adults Aged 18-90+

2022-01-20

Abstract excerpt

<h4>Background: </h4> Genetics play an important role in late-onset Alzheimer’s Disease (AD) etiology and dozens of genetic variants have been implicated in AD risk through large-scale GWAS meta-analyses. However, the precise mechanistic effects of most of these variants have yet to be determined. Deeply phenotyped cohort data can reveal physiological changes associated with genetic risk for AD across an age spect...

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Literature Corpus work: f793738a-54d7-51bf-a3d1-4cfcb4d0304d
DOI: 10.21203/rs.3.rs-1108842/v2

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