Article

HEIP1 is required for efficient meiotic crossover implementation and is conserved from plants to humans

2022-12-22

Abstract excerpt

Crossovers (CO) shuffle genetic information and physically connect homologous chromosome pairs, ensuring their balanced segregation during meiosis. COs arising from the major class I pathway require the activity of a well-conserved ZMMs group of proteins which, in conjunction with MLH1, facilitate the maturation of DNA recombination intermediates specifically into COs. The HEIP1 protein was identified in rice and...

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Literature Corpus work: f74c60af-f8cc-5f68-9b50-3bf4bb7187c6
DOI: 10.1101/2022.12.22.521598

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