Article
Crossover formation during rice meiosis relies on interaction of OsMSH4 and OsMSH5.
Genetics - 1 Dec 2014
Zhang Lei, Tang Ding, Luo Qiong, Chen Xiaojun, Wang Hongjun, Li Yafei, Cheng Zhukuan
Abstract excerpt
MSH4 encodes a MutS protein that plays a specialized role in meiosis. In eukaryotic species, such as budding yeast, mice, Caenorhabditis elegans, and Arabidopsis, msh4 mutants display meiotic defects with a reduced number of chiasmata. Here, we characterized rice MSH4 by map-based cloning. In Osmsh4 mutants, the chiasma frequency was dramatically decreased to ∼10% of the wild type, but the synaptonemal complex...
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