Article

CK2 directly controls CARD9 protein homeostasis

2025-02-07

Abstract excerpt

<h4>SUMMARY</h4> CARD9 is an attractive target for therapeutic intervention because the human genetic data provides strong evidence for the causal role of CARD9 in both protection and susceptibility to autoimmune disease. Expression quantitative trait loci (eQTLs) link higher CARD9 expression to increased disease risk and lower CARD9 expression to protection. Additionally, a rare allele variant leading to a C-ter...

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Literature Corpus work: f7346ec1-81e8-530e-b447-dd4c5c005e69
DOI: 10.1101/2025.02.03.636288

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